Research Library
The IAD Blog
Technical deep-dives into peptide biochemistry, signaling pathways, analytical chemistry, and research protocols. Written for laboratory researchers.
For research purposes only. Not for human consumption.
Lyophilized Peptide Handling: Storage Conditions, Reconstitution, and Stability Data
A practical research guide to lyophilized peptide handling protocols — covering lyophilization chemistry, appropriate reconstitution solvents, storage temperature regimens, degradation pathways, and stability data from published pharmaceutical literature.
HPLC and Mass Spectrometry: How Certificates of Analysis Verify Peptide Identity and Purity
A technical guide to interpreting peptide certificates of analysis (COAs), covering reversed-phase HPLC purity methodology, ESI-MS and MALDI-TOF identity confirmation, and what separates research-grade from substandard peptide material.
GHK-Cu: Copper Coordination Chemistry and Transcriptomic Analysis
An in-depth research review of GHK-Cu (glycyl-L-histidyl-L-lysine copper(II)), covering copper coordination geometry, redox chemistry, and transcriptomic profiling studies revealing its effects on gene expression networks in vitro.
Retatrutide (LY3437943): Multi-Receptor Pharmacology Across GLP-1R, GIPR, and GCGR
A pharmacological analysis of retatrutide (LY3437943), a triple agonist peptide targeting GLP-1R, GIPR, and GCGR. Covers receptor binding kinetics, cAMP signaling, biased agonism, and current clinical research data.
TB-500: Actin Sequestration, ILK Signaling, and Cytoskeletal Dynamics
A mechanistic review of TB-500 (synthetic Thymosin β4 fragment) research, focusing on G-actin sequestration, ILK/PINCH/parvin signaling at integrin adhesions, and cytoskeletal remodeling in preclinical research models.
BPC-157: NO/VEGF Pathway Signaling and FAK-Paxillin Axis Research
A mechanistic review of BPC-157 (Body Protection Compound-157) research, covering its interactions with nitric oxide synthase, VEGF receptor signaling, and the FAK-paxillin focal adhesion axis in preclinical models.
Research Peptides 101: Molecular Structure, Synthesis, and Classification
A technical overview of peptide biochemistry — from primary sequence and conformational geometry to solid-phase synthesis and purity validation for laboratory research.